Evaluation Of The Quality Of Locally Manufactured Antimicrobial Susceptibility Testing Discs Used In South Eastern Nigeria

摘要: Locally manufactured antimicrobial susceptibility discs are becoming increasingly used in both private and government hospital laboratories Nigeria. Data on the quality of these locally not available. In order to provide some data, we evaluated three brands common use southeastern The Brodisk, Jirehdisk Optudisc. performances agar disc diffusion assay against clinical isolates Staphylococcus aureus, Pseudomonas aeruginosa Escherichia coli were compared with that Abtek, imported brand. Un-interpretable zones inhibition defined as large merged together or complete wiping out bacterial growth at time reading plate, Optudisc Jiredisk brands. brand, did produce any such results. While Gentamycin Abtek produced a mean diameter zone 15mm, 19mm 16mm S. P. E. respectively, same antibiotic stated potency Brodisk an no test bacteria. Amoxylin Augmentin 13mm and 21mm aureus respectively. strain while un-interpretable result. Of made brands, is only one conformed international standard having more than eight per 90mm plate. our opinion, can be recommended for Nigeria further improvement. outcome this study indicates need improved standardization production discs. African Journal Clinical Experimental Microbiology Vol. 9 (3) 2008: pp. 122-128