Halogenated analogs of tri-O-thymotide (TOT) and tri-3-(2-butyl)-6-methylsalicylide (TSBS): synthesis and clathration studies.
作者： Jallal M. Gnaim , Philip M. Keehn , Bernard S. Green
DOI: 10.1016/S0040-4039(00)78886-1
关键词: Organic chemistry 、 Chemistry 、 Molecule 、 Halogen 、 Lactone 、 Tri-o-thymotide
摘要: Halogenated trisalicylide derivatives 1-6, representing three-fold symmetric C3 “home trimmers” as well dissymmetric C1 “mixed trimers” have been synthesized. Clathration studies indicate that these halogenated TOT analogs do not form clathrates. Reductive removal of the halogen was demonstrated for analog 2, providing a new entry to TOT-based host molecules.
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