Gastric and Duodenal Ethanol Concentrations after Intake of Alcoholic Beverages in Postprandial Conditions.
作者： Jari Rubbens , Danny Riethorst , Joachim Brouwers , Kris Wolfs , Erwin Adams
DOI: 10.1021/ACS.MOLPHARMACEUT.7B00252
关键词: Ingestion 、 Alcohol 、 Postprandial 、 Food science 、 Wine 、 Cmax 、 Stomach 、 Duodenum 、 Ethanol 、 Chemistry
摘要: This study determined intraluminal ethanol concentrations (stomach and duodenum) in fed healthy volunteers after the consumption of common alcoholic beverages (beer, wine, whisky). The results this were compared with a previous fasted volunteers. Five recruited crossover study. state was simulated by ingestion 250 mL Nutridrink Compact Neutral. Volunteers subsequently consumed two standard units beer (Stella Artois, 500 mL, 5.2% ethanol), wine (Blanc du Blanc, 200 11% or whisky (Gallantry Whisky, 80 40% ethanol). Gastric duodenal fluids aspirated through catheters over time analyzed for content head space gas chromatography. capability to permeate gastric rat mucosa examined an Ussing chambers setup. A similar average Cmax observed conditions: 3.3% 3.7% ethanol, respectively. condition am...
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