Hollow fiber membrane sample preparation devices

作者: Krishna Kallury , Joy Fan , Stig Pedersen-Bjergaard , Knut Rasmussen

DOI:

关键词: FiberSample preparationExtraction (chemistry)AnalytePolymerMaterials scienceChromatographyCoatingHollow fiber membraneMembrane

摘要: Simultaneous sample purification, enrichment and analysis of pharmaceuticals, illicit drugs, pollutants, biotechnological products, synthetic organic reaction products food/flavor ingredients from complex matrices can be performed using porous hollow fiber or porous-disk liquid-membrane devices. The devices are part a multi-well (e.g. 96-well) plate. used for selective separation mixtures containing trace levels analytes, in tandem with analytical instruments which routinely handle multiple samples under high throughput screening conditions. A multi-well/multi-vial plate into state-of-the-art HPLC GC sampling systems LC/MS GC/MS instruments. Samples enriched several orders magnitude directly withdrawn the injected chromatographic Alternatively, these introduced MS, CE other detection Selective extraction analytes achieved through variation acceptor phase chemistry, liquid membrane coating, pore size control fibers, nature polymer fibers made pH phase.

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