Pharmaceutical compositions for treatment of parkinson's disease and related disorders
作者： Dinesh K. Haswani , Peyman Moslemy , Avinash Nangia , Jules Jacob , Daya D. Verma
DOI:
关键词: Dosage form 、 Extended release 、 Pharmacology 、 Parkinson's disease 、 Drug 、 Enzyme inhibitor 、 Carbidopa 、 Bioadhesive 、 Medicine
摘要: The invention relates to the improvement in treatment of certain neural disorders / diseases, such as Parkinson's disease and other motor disorders. drug compositions dosage forms comprising said composition; methods manufacturing forms; treatment, administering composition form an individual. In embodiments, a decarboxylase enzyme inhibitor (e.g., carbidopa) extended release formulation is formulated with one or more bioadhesive polymers which may be useful for preferentially targeting at target absorption site. Upon administration patient, delivered desired tissue location proximal small intestine), released over period (preferably from after dinner morning after).
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