Ferriporphyrins and endothelium: a 2-edged sword-promotion of oxidation and induction of cytoprotectants.
作者： József Balla , György Balla , Viktoria Jeney , György Kakuk , Harry S. Jacob
DOI: 10.1182/BLOOD.V95.11.3442.011K51_3442_3450
关键词: Endothelial stem cell 、 Pharmacology 、 Heme 、 Endothelium 、 Heme arginate 、 Acute intermittent porphyria 、 Hemin 、 Biochemistry 、 Chemistry 、 Ferritin 、 Heme oxygenase
摘要: … , we examined the effects of ferriporphyrins with different hydrophobic properties on oxidant susceptibility of endothelial cells or LDL. We also tested ferriporphyrin's ability to induce the …
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bloodjournal.org参考文章(72)
Prem Ponka, Tissue-Specific Regulation of Iron Metabolism and Heme Synthesis: Distinct Control Mechanisms in Erythroid Cells Blood. ,vol. 89, pp. 1- 25 ,(1997) , 10.1182/BLOOD.V89.1.1
Treatment with Haematin in Acute Hepatic Porphyria QJM: An International Journal of Medicine. ,vol. 50, pp. 161- 174 ,(1981) , 10.1093/OXFORDJOURNALS.QJMED.A067678
G. M. Vercellotti, J. Balla, G. Balla, H. S. Jacob, J. Jessurun, M. B. Juckett, Ferritin protects endothelial cells from oxidized low density lipoprotein in vitro. American Journal of Pathology. ,vol. 147, pp. 782- 789 ,(1995)
R Glueck, D Green, I Cohen, CH Ts'ao, Hematin: unique effects of hemostasis Blood. ,vol. 61, pp. 243- 249 ,(1983) , 10.1182/BLOOD.V61.2.243.243
Gregory M Vercellotti, G. Balla, J. W. Eaton, H. S. Jacob, Iron loading of endothelial cells augments oxidant damage. Journal of Laboratory and Clinical Medicine. ,vol. 116, pp. 546- 554 ,(1990)
Elizabeth C. Theil, The Ferritin Family of Iron Storage Proteins Advances in Enzymology - and Related Areas of Molecular Biology. ,vol. 63, pp. 421- 449 ,(1990) , 10.1002/9780470123096.CH7
L. Y. Chau, T. S. Lee, L. J. Wang, R. C. Pai, F. Y. Lee, Expression of heme oxygenase-1 in atherosclerotic lesions. American Journal of Pathology. ,vol. 152, pp. 711- 720 ,(1998)
G Balla, H.S. Jacob, J Balla, M Rosenberg, K Nath, F Apple, J.W. Eaton, G.M. Vercellotti, Ferritin: a cytoprotective antioxidant strategem of endothelium. Journal of Biological Chemistry. ,vol. 267, pp. 18148- 18153 ,(1992) , 10.1016/S0021-9258(19)37165-0
A. Agarwal, J. Balla, G. Balla, A. J. Croatt, G. M. Vercellotti, K. A. Nath, Renal tubular epithelial cells mimic endothelial cells upon exposure to oxidized LDL. American Journal of Physiology-renal Physiology. ,vol. 271, ,(1996) , 10.1152/AJPRENAL.1996.271.4.F814
J M Gutteridge, A Smith, Antioxidant protection by haemopexin of haem-stimulated lipid peroxidation. Biochemical Journal. ,vol. 256, pp. 861- 865 ,(1988) , 10.1042/BJ2560861