Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures.
作者： Sarah Streck , Henriette Neumann , Hanne Mørck Nielsen , Thomas Rades , Arlene McDowell
DOI: 10.1016/J.IJPX.2019.100030
关键词: Microfluidics 、 Dispersity 、 Nanoparticle 、 PLGA 、 Polymer 、 Chemical engineering 、 Glycolic acid 、 Surface charge 、 Surface modification 、 Materials science
摘要: … Here, we optimize a bulk nanoprecipitation method using design of experiments and translate to a microfluidic device to formulate surface-modified poly-lactic-co-glycolic (PLGA) …
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