Carotenoids in cancer chemoprevention.

摘要: Various natural carotenoids, besides β-carotene, were proven to have anticarcinogenic activity, and some of them showed more potent activity than β-carotene. Thus, these carotenoids (α-carotene, lutein, zeaxanthin, lycopene, rbeta β-cryptoxanthin, fucoxanthin, astaxanthin, capsanthin, crocetin phytoene), as well may be useful for cancer prevention. In the case phytoene, concept 'bio-chemoprevention', which means biotechnology-assisted method chemoprevention, applicable. fact, establishment mammalian cells producing phytoene was succeeded by introduction crtB gene, encodes synthase, acquire resistance against carcinogenesis. Antioxidative phytoene-containing animal foods classified a novel type functional food, has preventive carcinogenesis, ability reduce accumulation oxidative damages, are hazardous human health.