Three withanolides from Withania coagulans
作者： Atta-ur-Rahman , Muhammad Shabbir , Muhammad Yousaf , Samina Qureshi , Dur e-Shahwar
DOI: 10.1016/S0031-9422(99)00416-1
关键词: Withanolide 、 Steroid 、 Biology 、 Stereochemistry 、 Polycyclic compound 、 Withania coagulans 、 Lactone
摘要: Abstract Three new withanolides, coagulins P, Q and R, were isolated from the whole plant of Withania coagulans. Their structures determined as 20,27-dihydroxy-3β-(O-β- D -glucopyranosyl)-1-oxo-(20S,22R)-witha-5,14,24-trienolide, 1α,20-dihydroxy-3β-(O-β- -glucopyranosyl)-(20S,22R)-witha-5,24-dienolide 3β,17β-dihydroxy-14,20-epoxy-1-oxo-(22R)-witha-5,24-dienolide by a combination 1D- 2D-NMR mass spectroscopic studies.
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