Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification.

作者: Guido Reifenberger , Katrin Lamszus , Lasse Dührsen , Cecile L Maire , Markus Glatzel

DOI: 10.1093/NEUONC/NOAB012

关键词: ProteomicsDNA methylationLiquid biopsyExtracellular vesicleDNAGliomaComputational biologyMethylationProteomeBiology

摘要: … in EVs secreted by glioblastoma cells, by using super-resolution single-… gliomas is maintained in the EV-DNA, indicating that EV profiling can predict the methylation class and MGMT …

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