Formulation of sub‐micron emulsions containing docosahexaenoic acid esterified in triacylglycerols or phospholipids

作者: Tin-Hinan Kabri , Anne Meynier , Delphine Bontemps , Cédric Gaillard , Loic Foucat

DOI: 10.1002/EJLT.201300045

关键词: Molecular diffusionPolyunsaturated fatty acidLecithinChromatographyPhospholipidChemistryFatty acidDocosahexaenoic acidPhosphatidylcholineEmulsion

摘要: In food applications, long-chain PUFA can be carried by different lipid molecules, which affect their end-use properties. The objective of this study was to formulate emulsions containing DHA located exclusively in phospholipids (PL-DHA) or triacylglycerols (TAG-DHA) and with similar fatty acid profiles organization. Food grade oils lecithins were blended on the basis (FA) contents submitted high-pressure homogenization mineral water. lecithin PL-DHA allowed stabilize oil-in-water emulsion droplet average diameter around 240 nm thank interfacial molecular packing PL species comprising lyso anionic phospholipids. Small particles 40 nm also highlighted transmission electron microscopy (TEM). To TAG-DHA mainly soybean phosphatidylcholine, Tween-80 selected among other co-emulsifiers. This presented an 203 nm contained small (20 nm) viewed TEM. It had less negative charge lower supramolecular diffusion coefficient than emulsion. physically stable whose size distribution remained unchanged during at least 19 days 37°C concomitantly increase 1H NMR FA coefficient. Practical applications: sub-micron designed storage. They prepared food-grade characterized compositions structures. used as delivery systems responding nutritional recommendations.

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