作者: M. Suker , C. Ince , C. van Eijck
DOI: 10.1007/978-3-319-13761-2_38
关键词: Hypoxemia 、 Tissue oxygen 、 Anaerobic exercise 、 Hypovolemia 、 Critical illness 、 Intensive care medicine 、 Medicine 、 Skeletal muscle 、 High altitude hypoxia 、 Insulin resistance
摘要: Extreme exercise has been used to study how normal physiology responds states that resemble critical illness, such as hypoxemia and hypovolemia. Studies of the Everest Research Group have shown body can tolerate by using adaptation mechanisms. One these mechanisms was found in lowlanders who climbed Mount Everest, mirroring illness. There an increase nitric oxide (NO) blood response hypoxic environment. These enhanced NO levels were associated with changes microcirculatory flow, which may affect local tissue oxygen delivery (DO2) [1]. Indeed extreme protect adapting cope This is seen skeletal muscle function, high altitude hypoxia inducing atrophy despite unchanged metabolites [2]. Another gluco-insular regulation, which, insulin resistance sustained hypoxia, glucose remain stable [3]. From considerations, it be concluded lessons learned, relevant critically ill patients need hypoxia. Indeed, fitness might even hold potential on ‘train’ surgery chapter explores this idea speculates insight benefit at risk for