Ectopic application of the repressive histone modification H3K9me2 establishes post-zygotic reproductive isolation in Arabidopsis thaliana .

摘要: Hybrid seed lethality as a consequence of interspecies or interploidy hybridizations is major mechanism reproductive isolation in plants. This manifested the endosperm, dosage-sensitive tissue supporting embryo growth. Deregulated expression imprinted genes such ADMETOS (ADM) underpin hybridization barrier Arabidopsis thaliana; however, mechanisms their action remained unknown. In this study, we show that ADM interacts with AT hook domain protein AHL10 and SET domain-containing SU(VAR)3-9 homolog SUVH9 ectopically recruits heterochromatic mark H3K9me2 to AT-rich transposable elements (TEs), causing deregulated neighboring genes. Several hybrid incompatibility identified Drosophila encode for heterochromatin-interacting proteins, which has led suggestion incompatibilities evolve divergence selfish DNA regulation. Our data imbalance chromatin regulators underpins Arabidopsis, suggesting epigenetic regulation TEs conserved feature animals