Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis.

作者: Zheng You , Satoshi Omura , Haruo Ikeda , David E. Cane

DOI: 10.1021/JA061469I

关键词: StreptomycesStreptomyces avermitilisDioxygenaseBiosynthesisStereochemistryChemistryGene clusterEnzyme kineticsMolecular cloningEscherichia coliBiochemistry

摘要: … in the conversion of pentalenene to pentalenolactone have been isolated from cultures of a wide variety of pentalenolactone-producing Streptomyces species. Pentalenolactone F (4) …

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