Serum uric acid level increases in proportion to the severity of pulmonary thromboembolism.
作者： Yoshito Shimizu , Noritoshi Nagaya , Toru Satoh , Masaaki Uematsu , Shingo Kyotani
DOI: 10.1253/CIRCJ.66.571
关键词: Serum uric acid level 、 Right heart catheterization 、 Pulmonary arterial pressure 、 Medicine 、 Internal medicine 、 Cardiology 、 Serum uric acid 、 Oxidative metabolism 、 Cardiac output 、 After treatment 、 In patient 、 Surgery
摘要: Serum uric acid (UA) has been proposed as a marker for impaired oxidative metabolism and the present study investigated whether serum UA level increases in proportion to severity of pulmonary thromboembolism (PTE) 193 patients. was repeatedly measured after treatment PTE 76 Right heart catheterization performed subgroup patients (n=104). on admission significantly elevated with acute (6.2±2.3 mg/dl) those chronic (7.0±2.1 compared age-matched controls (4.5±0.9 mg/ml). In particular, markedly higher 27 who died during hospitalization than remaining survivors (8.3 ±2.2 vs 6.5±2.2 mg/dl, p<0.001). PTE, negatively correlated cardiac output, but not mean arterial pressure. output positively decreased from 6.7±2.0 5.8 ±1.9 mg/dl treatment, associated an increase PaO2. thereby may serve potential indicator efficacy PTE. (Circ J 2002; 66: 571 - 575)
sci-hub.se 参考文章(34)
Takayuki Yoshinaga, Satoshi Ikeda, Eri Nishimura, Kosuke Shioguchi, Masahiro Shikuwa, Yoshiyuki Miyahara, Shigeru Kohno, Diagnostic value of pulsed Doppler echocardiography in acute pulmonary thromboembolism--comparison with pulmonary angiography and pulmonary artery pressure. Japanese Circulation Journal-english Edition. ,vol. 65, pp. 171- 176 ,(2001) , 10.1253/JCJ.65.171
Elliott M. Antman, James D. Marsh, Laurence H. Green, William Grossman, Blood oxygen measurements in the assessment of intracardiac left to right shunts: A critical appraisal of methodology American Journal of Cardiology. ,vol. 46, pp. 265- 271 ,(1980) , 10.1016/0002-9149(80)90068-5
J.R. Benotti, I.S. Ockene, J.S. Alpert, J.E. Dalen, The Clinical Profile of Unresolved Pulmonary Embolism Chest. ,vol. 84, pp. 669- 678 ,(1983) , 10.1378/CHEST.84.6.669
Norihisa Kumasaka, Masahito Sakuma, Kunio Shirato, Incidence of pulmonary thromboembolism in Japan. Japanese Circulation Journal-english Edition. ,vol. 63, pp. 439- 441 ,(1999) , 10.1253/JCJ.63.439
LEWIS STEPHEN PILCHER, DAVID BOGART PILCHER, Lewis Stephen Pilcher, founding editor of the Annals of Surgery. Editor for 50 consecutive years. Annals of Surgery. ,vol. 201, pp. 5- 10 ,(1985) , 10.1097/00000658-198501000-00003
James E. Dalen, Joseph S. Alpert, Natural history of pulmonary embolism Progress in Cardiovascular Diseases. ,vol. 17, pp. 259- 270 ,(1975) , 10.1016/S0033-0620(75)80017-X
K M Moser, W R Auger, P F Fedullo, Chronic major-vessel thromboembolic pulmonary hypertension. Circulation. ,vol. 81, pp. 1735- 1743 ,(1990) , 10.1161/01.CIR.81.6.1735
Jack Hirsh, John Hoak, Management of Deep Vein Thrombosis and Pulmonary Embolism: A Statement for Healthcare Professionals From the Council on Thrombosis (in Consultation With the Council on Cardiovascular Radiology), American Heart Association Circulation. ,vol. 93, pp. 2212- 2245 ,(1996) , 10.1161/01.CIR.93.12.2212
Sergio Dalla-Volta, Antonio Palla, Annamaria Santolicandro, Carlo Giuntini, Vittorio Pengo, Odoardo Visioli, Pietro Zonzin, Domenico Zanuttini, Franco Barbaresi, Giancarlo Agnelli, Mario Morpurgo, Maria Giulia Marini, Luigi Visani, PAIMS 2: Alteplase combined with heparin versus heparin in the treatment of acute pulmonary embolism. Plasminogen activator Italian multicenter study 2 Journal of the American College of Cardiology. ,vol. 20, pp. 520- 526 ,(1992) , 10.1016/0735-1097(92)90002-5
STUART RICH, SIDNEY LEVITSKY, BRUCE H BRUNDAGE, Pulmonary Hypertension from Chronic Pulmonary Thromboembolism Annals of Internal Medicine. ,vol. 108, pp. 425- 434 ,(1988) , 10.7326/0003-4819-108-3-425