作者: Michal Goetz , Antonin Sebela , Marketa Mohaplova , Silvie Ceresnakova , Radek Ptacek
关键词: Bipolar disorder 、 High risk offspring 、 Psychiatric diagnosis 、 Offspring 、 Mean age 、 Psychiatry 、 Psychopathology 、 Clinical psychology 、 Quality of life 、 Psychology
摘要: Abstract Objective: To determine current and lifetime psychopathology assess quality of life (QoL) in offspring a parent with bipolar disorder (BD). Methods: We investigated 43 parents (high-risk [HRO]) (mean age 12.5 ± 3.1; range 6.7–17.9 years) comparison matched for sex, age, IQ healthy parents. Lifetime presence Diagnostic Statistical Manual Mental Disorders, 5th ed. (DSM-5) diagnoses were assessed using Kiddie-Schedule Affective Disorders Schizophrenia-Present Version (K-SADS-PL). administered self-report versions General Behavior Inventory the Screen Child Anxiety-Related Emotional (SCARED). QoL was evaluated questionnaire KIDSCREN-52. Results: Thirty-seven HRO (86%) 18 controls (42%) met DSM-5 criteria at least one psychiatric diagnosis (adjusted OR = 7.20; 95% CI 2.27–22.81). Compared to controls, had higher ...