Effects of maxillomandibular advancement on the upper airway and surrounding structures in patients with obstructive sleep apnoea: a systematic review

摘要: Obstructive sleep apnoea is ideally treated by continuous positive airway pressure, but other options are needed because its clinical effectiveness limited poor acceptance and tolerance, which results in suboptimal compliance. Patients often prefer operation, with maxillomandibular advancement (MMA) being the most effective approach. In this systematic review we have assessed effects on upper surrounding structures patients obstructive apnoea. After a structured search of electronic databases hand searching, retrieved 104 publications. application inclusion exclusion criteria, 15 studies remained. From these extracted data study design, sample size, patients, methods measurement, outcomes. The quality each was objectively. heterogeneity samples outcome measures prevented meta-analysis. MMA shown to be an treatment Primary secondary resulted mean reductions apnoea-hypopnoea index/respiratory disturbance index 61-92% 82-92%, respectively. operation not only enlarges anteroposterior lateral dimensions, also raises hyoid. Only 7 reported relations between improvement changes structures, one correlated it skeletal advancement. were low or medium quality. There insufficient support relation contradictory studies.