Evaluate the diagnosis of neonatal sepsis by measuring interleukins: A systematic review.

作者: Hassan Boskabadi , Maryam Zakerihamidi

DOI: 10.1016/J.PEDNEO.2017.10.004

关键词: Cochrane LibraryMedicineSepsisProspective cohort studyRetrospective cohort studyIntensive care medicineInterleukinCommon diseaseInternal medicineHigh morbidityNeonatal sepsis

摘要: Neonatal sepsis is a dangerous and common disease among infants which associated with high morbidity mortality. Interleukins may be helpful for diagnosis of neonatal sepsis. Therefore, this study conducted to investigate the role interleukins in In study, databases including PubMed, Cochrane Library, ISI Google Scholar were searched up 2016. Keywords were: Sepsis, neonatal, interleukins, prediction diagnosis. Study inclusion criteria Articles about relationship between interleukins; studies on babies; English Persian articles enough information from test results. that had focused adult or used other markers except ILs just their abstracts available excluded study. Of 100 studies, eventually, 16 considered 12 prospective 3 cross-sectional 1 retrospective IL6 has been studied more than (50% articles). 6, 8 10 are initial above 68 pg/ml 85% sensitivity 80% specificity, IL8 269.51 pg/ml 50% IL10 27 pg/ml 60% 87% specificity combined 186.83 pg/ml 75.63% 71.49% can based results most

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