Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test.

作者: Hirotaka Shoji , Tsuyoshi Miyakawa

DOI: 10.1186/S13041-020-00721-2

关键词: Internal medicineC57bl 6jElevated plus mazeGeneral healthBehavioral testNeurological functionPlasma corticosteroneOpen fieldEndocrinologyTest (assessment)Medicine

摘要: The elevated plus maze test is a widely used test for assessing anxiety-like behavior and screening novel therapeutic agents in rodents. Previous studies have shown that a variety of …

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