The incorporation and removal of large amounts of strontium by physiologic mechanisms in mineralized tissues of the rat

作者: A. R. Johnson , W. D. Armstrong , Leon Singer

DOI: 10.1007/BF02279212

关键词: BiochemistrySodiumMetabolismStrontiumInternal medicinePotassiumExcretionCalciumMineralized tissuesOsteoidEndocrinologyChemistry

摘要: The incorporation and removal of strontium from the bones teeth rats under conditions low high dietary levels were investigated. In an otherwise satisfactory diet, amount equimolar to that calcium seriously debilitates young growing rat may culminate in death. pathology due was found by methods used only hard tissues. excess osteoid formed originally presence large amounts is removed during a subsequent period feeding on regimen. Strontium participation physiologic processes appears be two types, (a) excretion body, (b) incarceration within translocation incisor has been demonstrated. Differences sodium potassium contents hemi-mandibulae experimental control groups also observed.

参考文章(12)
Albert Edward Sobel, Julius Cohen, Benjamin Kramer, The nature of the injury to the calcifying mechanism in rickets due to strontium Biochemical Journal. ,vol. 29, pp. 2640- 2645 ,(1935) , 10.1042/BJ0292640
E.P. Clark, J.B. Collip, A STUDY OF THE TISDALL METHOD FOR THE DETERMINATION OF BLOOD SERUM CALCIUM WITH A SUGGESTED MODIFICATION Journal of Biological Chemistry. ,vol. 63, pp. 461- 464 ,(1925) , 10.1016/S0021-9258(18)85009-8
Norman S. MacDonald, Ralph E. Nusbaum, Richard. Stearns, Florita. Ezmirlian, Clare. McArthur, Patricia. Spain, The skeletal deposition of non-radioactive strontium. Journal of Biological Chemistry. ,vol. 188, pp. 137- 143 ,(1951) , 10.1016/S0021-9258(18)56154-8
W. HOLGATE, R. H. MOLE, JANET VAUGHAN, Accumulation of strontium-90 in dental tissues. Nature. ,vol. 182, pp. 1294- 1295 ,(1958) , 10.1038/1821294B0
WILLIAM F. NEUMAN, MARGARET W. NEUMAN, The chemical dynamics of bone mineral The American Journal of the Medical Sciences. ,vol. 238, pp. 789- ,(1959) , 10.1097/00000441-195912000-00030
A. R. Johnson, W. D. Armstrong, L. Singer, Strontium Incorporation into Dental Enamel Science. ,vol. 153, pp. 1396- 1397 ,(1966) , 10.1126/SCIENCE.153.3742.1396
Leon Singer, W.D. Armstrong, L.M. Colman, Microdetermination of calcium in biological materials Analytical Biochemistry. ,vol. 9, pp. 217- 223 ,(1964) , 10.1016/0003-2697(64)90106-X
Arne Engström, Bone and radiostrontium ,(1958)
Cyrus H. Fiske, Yellapragada Subbarow, THE COLORIMETRIC DETERMINATION OF PHOSPHORUS Journal of Biological Chemistry. ,vol. 66, pp. 375- 400 ,(1925) , 10.1016/S0021-9258(18)84756-1