Chemopotentiation by PARP inhibitors in cancer therapy
作者： Lucio Tentori , Grazia Graziani
DOI: 10.1016/J.PHRS.2005.02.010
关键词: DNA repair 、 Topoisomerase-II Inhibitor 、 Topoisomerase-I Inhibitor 、 Cancer research 、 DNA damage 、 Biochemistry 、 Chromatin 、 Biology 、 Poly (ADP-Ribose) Polymerase Inhibitor 、 Poly ADP ribose polymerase 、 Base excision repair
摘要: … be promptly stimulated by DNA strand breakages. The role of PARP-1 in facilitating DNA repair of … Both enzymes detect DNA strand interruptions acting as nick sensors, providing rapid …
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