Fracture-related infections in HIV infected patients: A systematic review and meta-analysis
作者： Luan Nieuwoudt , Reitze N. Rodseth , Leonard Charles Marais
DOI: 10.1016/J.JOR.2020.01.023
关键词: Cochrane Library 、 Internal medicine 、 MEDLINE 、 Meta-analysis 、 Human immunodeficiency virus (HIV) 、 Incidence (epidemiology) 、 Hiv infected patients 、 Prospective cohort study 、 Medicine 、 Acquired immunodeficiency syndrome (AIDS)
摘要: Abstract Aim To conduct a systematic review and meta-analysis comparing the incidence of fracture-related infections (FRI) following surgical management closed open fractures in HIV-positive HIV-negative patients. Methods A literature search was conducted using MEDLINE, ProQuest, Web Science, The Cochrane Library Scopus. Our own files reference lists identified key articles were also searched. We included studies where primary outcome development FRI patients with fractures. Results Eleven for data synthesis. had non-significant increase when compared to (in combined). Open treated pre-antiretroviral era 5.6 times greater risk developing FRI. In post-antiretroviral (1997 onwards) did not have than both small retrospective natures these studies, together heterogeneous definitions used, are limitations this study. Conclusion While there few large prospective available suggests that before introduction antiretroviral therapy HIV infection associated infected show an increased
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