Cell Adhesion to Ion Implanted Titanium

作者: K. S. Grabowski , C. R. Gossett , F. A. Young , J. C. Keller

DOI: 10.1557/PROC-110-697

关键词: Ion implantationX-ray photoelectron spectroscopyCell adhesionMaterials scienceScanning electron microscopeTitaniumIonNuclear chemistryAdhesionTissue Adhesion

摘要: This preliminary investigation evaluates the influence of ion implantation on tissue adhesion by measuring tendency fibroblasts to attach surface implanted Ti. For this work, polished specimens commercially pure Ti were with ions Ti, Ca, C, or N produce a concentration element up about 25 at. %. Unimplanted and ASTM treated culture plate prepared as controls. Specimens sterilized, then exposed for 15 min. medium containing 100,000 fibroblasts. The solution loose rinsed away counted determine those left attached. different protocols fibroblast will be described. Analysis structure composition surfaces was obtained scanning electron microscopy, x-ray photoelectron spectroscopy, elastic backscattering spectrometry energetic He ions.

参考文章(4)
Lawrence R. Doolittle, Algorithms for the rapid simulation of Rutherford backscattering spectra Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. ,vol. 9, pp. 344- 351 ,(1985) , 10.1016/0168-583X(85)90762-1
C.M. Davisson, IMPLNT — A fortran program to calculate the distribution of implanted ions which includes the effects due to sputtering Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms. ,vol. 13, pp. 421- 425 ,(1986) , 10.1016/0168-583X(86)90540-9
J.P. Biersack, L.G. Haggmark, A Monte Carlo computer program for the transport of energetic ions in amorphous targets Nuclear Instruments and Methods. ,vol. 174, pp. 257- 269 ,(1980) , 10.1016/0029-554X(80)90440-1
P. Sioshansi, Medical applications of ion beam processes Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. ,vol. 19-20, pp. 204- 208 ,(1987) , 10.1016/S0168-583X(87)80043-5