Modern Anti-Tuberculosis Drugs and Their Classification. Part I: First-Line Drugs

作者: L. A. Kayukova , E. A. Berikova

DOI: 10.1007/S11094-020-02239-2

关键词: Tb controlEffective treatmentAnti tuberculosisTuberculosisChemistryPharmacology toxicologyFirst linePharmacyInternal medicine

摘要: The historical classification (1993) of anti-tuberculosis drugs included three (I-III) lines that were subdivided into five groups (2006). duration treatment drug-sensitive (DS) tuberculosis (TB) with first-line is 6 – 12 months; multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) second-line drugs, 18 months longer. Directly Observed Treatment Short course (DOTS) DOTS-Plus therapies are measures world control. Based on the need for more effective MDR XDR TB, 2016 introduced six (A-C D1-D3) in connection development new anti-TB drugs. present review presents preparations their derivatives possessing activity against DS (DR) M. strains.

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