Influence of the quantity of sunscreen applied on the ability to protect against ultraviolet‐induced polymorphous light eruption

作者: Robert Bissonnette , Simon Nigen , Chantal Bolduc

DOI: 10.1111/J.1600-0781.2012.00678.X

关键词: DermatologyBroad spectrumPolymorphous light eruptionFemale patientMedicineUltravioletSun protection factor

摘要: Summary Background/Purpose Despite the fact that most people apply less sunscreen than 2 mg/cm2 required to measure sun protection factor (SPF), there is a lack of clinical data on afforded from lower applied quantities. The aim this study was compare ability sunscreens protect against UV-induced polymorphous light eruption (PLE) when at and 1 mg/cm2. Methods Two SPF 45 (one with high level one low UVA protection) were 1 mg/cm2 four randomized 6 × 6 cm areas upper thorax 15 female patients typical history PLE. exposed daily increasing UVA–UVB radiation until PLE reaction detected or maximum five consecutive days. Results The proportion who developed UVA-protection significantly (0%) (73%) both (P = 0.004). At 1 mg/cm2, 33% 80% presented sunscreen, respectively (P = 0.064). Conclusion A broad spectrum able majority development even 1 mg/cm2.

参考文章(18)
Wulf Hc, Bech-Thomsen N, Sunbathers' application of sunscreen is probably inadequate to obtain the sun protection factor assigned to the preparation. Photodermatology, Photoimmunology and Photomedicine. ,vol. 9, pp. 242- 244 ,(1992)
Morison Wl, Stern Rs, Polymorphous light eruption: a common reaction uncommonly recognized. Acta Dermato-venereologica. ,vol. 62, pp. 237- ,(1982)
R. Bimczok, H. Gers-Barlag, C. Mundt, E. Klette, S. Bielfeldt, T. Rudolph, F. Pflücker, U. Heinrich, H. Tronnier, W. Johncock, B. Klebon, H. Westenfelder, H. Flöβer-Müller, K. Jenni, D. Kockott, J. Lademann, B. Herzog, M. Rohr, Influence of applied quantity of sunscreen products on the sun protection factor--a multicenter study organized by the DGK Task Force Sun Protection. Skin Pharmacology and Physiology. ,vol. 20, pp. 57- 64 ,(2007) , 10.1159/000096173
Robert Bissonnette, Soraya Allas, Dominique Moyal, Nathalie Provost, Comparison of UVA protection afforded by high sun protection factor sunscreens. Journal of The American Academy of Dermatology. ,vol. 43, pp. 1036- 1038 ,(2000) , 10.1067/MJD.2000.109299
Sergio Schalka, Vitor Manoel Silva dos Reis, Luis Carlos Cucé, The influence of the amount of sunscreen applied and its sun protection factor (SPF): evaluation of two sunscreens including the same ingredients at different concentrations Photodermatology, Photoimmunology and Photomedicine. ,vol. 25, pp. 175- 180 ,(2009) , 10.1111/J.1600-0781.2009.00408.X
Bernhard Ortel, Adrian Tanew, Klaus Wolff, Herbert Hönigsmann, Polymorphous light eruption: Action spectrum and photoprotection Journal of the American Academy of Dermatology. ,vol. 14, pp. 748- 753 ,(1986) , 10.1016/S0190-9622(86)70088-1
Sharam Samson Yashar, Henry W. Lim, Classification and evaluation of photodermatoses. Dermatologic Therapy. ,vol. 16, pp. 1- 7 ,(2003) , 10.1046/J.1529-8019.2003.01601.X
Rachel Neale, Gail Williams, Adèle Green, Application patterns among participants randomized to daily sunscreen use in a skin cancer prevention trial. Archives of Dermatology. ,vol. 138, pp. 1319- 1325 ,(2002) , 10.1001/ARCHDERM.138.10.1319