Cumulative Burden of Colorectal Cancer Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

作者: Alexi N Archambault , Yu-Ru Su , Jihyoun Jeon , Minta Thomas , Yi Lin

DOI: 10.1053/J.GASTRO.2019.12.012

关键词: CancerCohort studyFamily historyCase-control studyOncologyPopulationCohortLynch syndromeInternal medicineOdds ratioMedicine

摘要: … Participants for this study were pooled from 3 large consortia that provided clinical and genotyping data: the Colon Cancer Family Registry, the Colorectal Transdisciplinary Study, and …

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