The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas
作者： Shan Liang , Zhulin Yang , Daiqiang Li , Xiongying Miao , Leping Yang
DOI: 10.1155/2015/379568
关键词: Nectin 、 Biology 、 Adenocarcinoma 、 Disease 、 Cell adhesion molecule 、 Stage (cooking) 、 Survival analysis 、 Pathological 、 Immunohistochemistry 、 Pathology
摘要: Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease, but the genetic basis of PDAC still unclear. In this study, Nectin-2 and DDX3 expression in 106 PDAC, 35 peritumoral tissues, 55 benign pancreatic lesions, 13 normal tissues were measured by immunohistochemical methods. Results showed that percentage positive was significantly higher tumors than (P < 0.01). The cases with lower patients without lymph node metastasis invasion having TNM stage I/II disease metastasis, invasion, III/IV 0.05 or P Positive associated poor differentiation PDAC. Kaplan-Meier survival analysis 0.001). Cox multivariate revealed independent prognosis factors patients. conclusion, are progression
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