Doppler derived quantitative flow estimate in coronary artery bypass graft: A computational multiscale model for the evaluation of the current clinical procedure
作者： Raffaele Ponzini , Massimo Lemma , Umberto Morbiducci , Franco M. Montevecchi , Alberto Redaelli
DOI: 10.1016/J.MEDENGPHY.2007.09.004
关键词: Simulation 、 Hemodynamics 、 Multiscale modeling 、 Current (fluid) 、 Doppler effect 、 Computer science 、 Volumetric flow rate 、 Applied mathematics 、 Flow (mathematics) 、 Instrumentation 、 Computational fluid dynamics
摘要: In order to investigate the reliability of so called mean velocity/vessel area formula adopted in clinical practice for estimation flow rate using an intravascular Doppler guide wire instrumentation, a multiscale computational model was used give detailed predictions on profiles within Y-shaped coronary artery bypass graft (CABG) models. At this purpose three CABG models were built from patient's data and evaluate compare, each model, computed estimated according assumption parabolic velocity profile. A consistent difference between exact value found every branch all study we showed that discrepancy is coherent theory Womersley regarding spatial unsteady conditions. particular work put evidence error can be reduced by recently proposed Ponzini et al. [Ponzini R, Vergara C, Redaelli A, Veneziani A. Reliable CFD-based haemodynamics measures. Ultrasound Med Biol 2006;32(10):1545-55], accounting nature blood, applicable without resorting further measurements.
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