IL-17 Signaling in the Tumor Microenvironment.
作者： R. M. Gorczynski
DOI: 10.1007/978-3-030-38315-2_4
关键词: Extracellular matrix 、 Cancer research 、 Metastasis 、 Stromal cell 、 Cytokine 、 Biology 、 Immune system 、 Interleukin 17 、 Tumor microenvironment 、 Cancer cell
摘要: Inflammation is recognized as representing a double-edged sword in terms of tumor growth, in some instances contributing to attenuation of growth and in others to enhanced progression and metastasis. Extracellular signals, released by cells within the tumor microenvironment (TME), including cancer cells themselves, as well as infiltrating immune cells, stromal cells, and other components of the extracellular matrix, all can contribute to reshaping the tumor microenvironment (TME) and tumor growth/survival. Most recently …
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sci-hub.st 参考文章(95)
Simone Punt, Jessica M Langenhoff, H Putter, Gert Jan Fleuren, Arko Gorter, Ekaterina S Jordanova, The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review OncoImmunology. ,vol. 4, pp. 1- 10 ,(2015) , 10.4161/2162402X.2014.984547
Yuqiang Ji, Wanggang Zhang, Th17 cells: positive or negative role in tumor? Cancer Immunology, Immunotherapy. ,vol. 59, pp. 979- 987 ,(2010) , 10.1007/S00262-010-0849-6
Xinming Su, Jian Ye, Eddy C. Hsueh, Yanping Zhang, Daniel F. Hoft, Guangyong Peng, Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells Journal of Immunology. ,vol. 184, pp. 1630- 1641 ,(2010) , 10.4049/JIMMUNOL.0902813
Zhi-Zhang Yang, Anne J. Novak, Steven C. Ziesmer, Thomas E. Witzig, Stephen M. Ansell, Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma. Cancer Research. ,vol. 69, pp. 5522- 5530 ,(2009) , 10.1158/0008-5472.CAN-09-0266
Ilona Kryczek, Rebecca Liu, Guobin Wang, Ke Wu, Xiaogong Shu, Wojciech Szeliga, Linhua Vatan, Emily Finlayson, Emina Huang, Diane Simeone, Bruce Redman, Theodore H. Welling, Alfred Chang, Weiping Zou, FOXP3 defines regulatory T cells in human tumor and autoimmune disease Cancer Research. ,vol. 69, pp. 3995- 4000 ,(2009) , 10.1158/0008-5472.CAN-08-3804
Antoine E. Karnoub, Ajeeta B. Dash, Annie P. Vo, Andrew Sullivan, Mary W. Brooks, George W. Bell, Andrea L. Richardson, Kornelia Polyak, Ross Tubo, Robert A. Weinberg, Mesenchymal stem cells within tumour stroma promote breast cancer metastasis Nature. ,vol. 449, pp. 557- 563 ,(2007) , 10.1038/NATURE06188
Alberto Mantovani, Pedro Romero, A Karolina Palucka, Francesco M Marincola, Tumour immunity: effector response to tumour and role of the microenvironment The Lancet. ,vol. 371, pp. 771- 783 ,(2008) , 10.1016/S0140-6736(08)60241-X
Lin Wang, Tangsheng Yi, Marcin Kortylewski, Drew M. Pardoll, Defu Zeng, Hua Yu, IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway Journal of Experimental Medicine. ,vol. 206, pp. 1457- 1464 ,(2009) , 10.1084/JEM.20090207
Nicholas J Wilson, Katia Boniface, Jason R Chan, Brent S McKenzie, Wendy M Blumenschein, Jeanine D Mattson, Beth Basham, Kathleen Smith, Taiying Chen, Franck Morel, Jean-Claude Lecron, Robert A Kastelein, Daniel J Cua, Terrill K McClanahan, Edward P Bowman, Rene de Waal Malefyt, Development, cytokine profile and function of human interleukin 17-producing helper T cells Nature Immunology. ,vol. 8, pp. 950- 957 ,(2007) , 10.1038/NI1497
Estelle Bettelli, Yijun Carrier, Wenda Gao, Thomas Korn, Terry B Strom, Mohamed Oukka, Howard L Weiner, Vijay K Kuchroo, None, Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. ,vol. 441, pp. 235- 238 ,(2006) , 10.1038/NATURE04753