Selected features of copper metabolism in the cat.

作者: Gloria Doong , Carl L. Keen , Quinton Rogers , James Morris , Robert B. Rucker

DOI: 10.1093/JN/113.10.1963

关键词: BiochemistrySpleenKittenCopperKidneyWeanlingEgg whiteAnimal scienceConnective tissueDismutaseChemistry

摘要: In separate experiments, domestic short hair kittens were fed diets based on soy or egg white protein containing from 1.98 to 9.64 0.58 9.8 micrograms Cu/g diet, respectively. Moreover, also nursed queens either 12 of diet. each experiment, copper was analyzed in liver, spleen, lung, heart, muscle and brain samples. The liver concentration the most responsive changes dietary intake. For example, weanling 24 45 micrograms/g wet weight, Likewise, levels hepatic Cu,Zn-superoxide dismutase reduced low However, concentrations zinc, iron manganese brain, kidney not consistently changed response intakes. Anemia a consistent feature copper-deficient cat kitten, but signs connective tissue lesions observed born weaned less than 1 Based these observations data for growth differing copper, requirement kitten estimated be 4-5 diet (energy content approximately 5 kcal 21 kJ per gram).

参考文章(16)
M. M. Wintrobe, G. S. Shields, D. A. Kimball, W. F. Coulson, W. H. Carnes, G. E. Cartwright, Studies on copper metabolism. 32. Cardiovascular lesions in copper-deficient swine. American Journal of Pathology. ,vol. 41, pp. 603- 621 ,(1962)
Shigemasa Osaki, Donald A. Johnson, Earl Frieden, The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human Serum Journal of Biological Chemistry. ,vol. 241, pp. 2746- 2751 ,(1966) , 10.1016/S0021-9258(18)96527-0
David I. Paynter, Reginald J. Moir, Eric J. Underwood, Changes in Activity of the Cu-Zn Superoxide Dismutase Enzyme in Tissues of the Rat with Changes in Dietary Copper The Journal of Nutrition. ,vol. 109, pp. 1570- 1576 ,(1979) , 10.1093/JN/109.9.1570
Karl E. Mason, A Conspectus of Research on Copper Metabolism and Requirements of Man The Journal of Nutrition. ,vol. 109, pp. 1979- 2066 ,(1979) , 10.1093/JN/109.11.1979
Guglielmo de Rosa, Carl L. Keen, Roland M. Leach, Lucille S. Hurley, Regulation of Superoxide Dismutase Activity by Dietary Manganese Journal of Nutrition. ,vol. 110, pp. 795- 804 ,(1980) , 10.1093/JN/110.4.795
Helene Swenerton, Lucille S. Hurley, Severe zinc deficiency in male and female rats. Journal of Nutrition. ,vol. 95, pp. 8- 18 ,(1968) , 10.1093/JN/95.1.8
J. L. Evans, P. A. Abraham, Anemia, Iron Storage and Ceruloplasmin in Copper Nutrition in the Growing Rat The Journal of Nutrition. ,vol. 103, pp. 196- 201 ,(1973) , 10.1093/JN/103.2.196
E. Kane, J. G. Morris, Q. R. Rogers, P. J. Ihrke, P. T. Cupps, Zinc deficiency in the cat. Journal of Nutrition. ,vol. 111, pp. 488- 495 ,(1981) , 10.1093/JN/111.3.488
Carl L. Keen, Lucille S. Hurley, Developmental changes in concentrations of iron, copper, and zinc in mouse tissues. Mechanisms of Ageing and Development. ,vol. 13, pp. 161- 176 ,(1980) , 10.1016/0047-6374(80)90059-7