Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.

作者: Alex Michotte , Yvette Michotte , Ann Massie , Anneleen Schallier , Ilse Smolders

DOI: 10.3233/JAD-2011-101005

关键词: BiologyMicrodialysisCortex (botany)BiochemistryEndocrinologySystem XGliosisInternal medicineHippocampal formationHippocampusGlutamate receptorGlutamate reuptake

摘要: … VGLUT3 and/or system xc − , can result in toxic extracellular glutamate levels and neuronal death. … for the elevation of extracellular glutamate concentrations and neuronal death in other …

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