Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids.
作者： Dermot Roden , Thomas M. Bosley , Barbara Fowble , James Clark , Peter J. Savino
DOI: 10.1016/S0161-6420(90)32582-4
关键词: Optic nerve 、 Lumbar puncture 、 Corticosteroid 、 Medicine 、 Eye disease 、 Radiation therapy 、 Optic chiasma 、 Chemotherapy 、 Surgery 、 Complication
摘要: Thirteen patients with delayed radiation injury to the optic nerves and chiasm were treated hyperbaric oxygen (HBO) corticosteroids. These experienced painless, abrupt loss of vision in one (6 patients) or both (7 eyes between 4 35 months after receiving doses at least 4500 cGy region chiasm. Diagnostic evaluation including neuro-imaging lumbar puncture showed no recurrent tumor other cause for visual loss. No patient's improved during treatment follow-up lasting 1 years. There serious complications treatment.
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