Physicochemical parameters of NO-containing gas flow affect wound healing therapy. An experimental study.
作者： Anatoly B. Shekhter , Alexander V. Pekshev , Andrey B. Vagapov , Vladimir I. Telpukhov , Peter V. Panyushkin
DOI: 10.1016/J.EJPS.2018.11.034
关键词: Skin wound 、 Atmospheric air 、 Chemistry 、 Wound healing 、 New device 、 Biomedical engineering 、 Nitric oxide 、 Nitric oxide therapy 、 Clinical Practice
摘要: Abstract Therapy of wounds and inflammatory diseases with NO-containing gas flows (NO-CGF) has proved to be effective in a longterm clinical practice. Plasma-chemical generation nitric oxide occurs from atmospheric air Plason device. For the purpose modification improvement NO-therapy, effects various physicochemical parameters NO-CGF on reparative processes were studied. Treatment planar full-thickness skin laboratory rats was analyzed morphological, immunohistochemical, morphometric statistical methods. The study showed that device experimental device, which differs by temperature, significantly reduce enhance regenerative wounds. an ambient temperature generated noticeably facilitated wound healing direct ration content flow velocity at area application. Temperature did not affect course process. development new for NO-therapy may use both physicians patients.
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