Particle dispersion and separation resolution of pinched flow fractionation.
作者： Abhishek Jain , Jonathan D. Posner
DOI: 10.1021/AC0713813
关键词: Chemistry 、 Particle size 、 Microchannel 、 Optics 、 Surface finish 、 Resolution (electron density) 、 Dispersion (chemistry) 、 Soft lithography 、 Particle 、 Aspect ratio (image)
摘要: This paper investigates a hydrodynamic particle separation technique that employs pinching of particles to narrow microchannel. The are subject sudden expansion which results in size-based transverse the flow direction. resolution and dispersion measured using epifluorescence microscopy. predicted compact theoretical model. Devices fabricated conventional soft lithography polydimethylsiloxane. show is function microchannel aspect ratio, size difference, sidewall roughness. A as large 3.8 obtained this work. work shows with diameters on order roughness cannot be separated pinched fractionation.
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