Pd(II)-catalyzed ortho-trifluoromethylation of arenes using TFA as a promoter.
作者： Xisheng Wang , Larry Truesdale , Jin-Quan Yu
DOI: 10.1021/JA909522S
关键词: Medicinal chemistry 、 Trifluoroacetic acid 、 Trifluoromethylation 、 Benzene 、 Electrophile 、 Organic chemistry 、 Palladium 、 Sodium trifluoromethanesulfinate 、 Reagent 、 Catalysis 、 Chemistry
摘要: … The presence of trifluoroacetic acid is crucial for this catalytic reaction. … However, we were pleased to find that the presence of 10 equiv of trifluoroacetic acid (TFA) in dichloroethane …
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