Isolation and characterization of two new drimanes from Zygogynum baillonii and synthesis of analogues

作者: Dalia Fomekong Fotsop , Fanny Roussi , Catherine Le Callonec , Hadjira Bousserouel , Marc Litaudon

DOI: 10.1016/J.TET.2007.12.022

关键词: BarkOrganic chemistryChemistryZygogynum bailloniiWinteraceaeStereochemistry

摘要: Abstract Two new drimanes were isolated and characterized from the bark of Zygogynum baillonii, an endemic New-Caledonian tree Winteraceae family. One it shows a significant cytotoxic activity. In order to define structure–activity relationships, analogues synthesized their cytotoxicity was evaluated.

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