Co-Delivery of Curcumin and Paclitaxel by "Core-Shell" Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer.

作者: Meng-Dan Zhao , Jun-Qin Li , Feng-Ying Chen , Wei Dong , Li-Juan Wen

DOI: 10.2147/IJN.S224579

关键词: NanocarriersCytotoxicityCD44Cancer researchOvarian cancerDrug resistanceCurcuminCancerPaclitaxelChemistry

摘要: … To understand the regulatory mechanism of resistance and measure the anti-tumor efficacy of the treatments, cytotoxicity assay, cellular uptake, P-glycoprotein (P-gp) expression and …

参考文章(49)
Meng-Dan Zhao, Yan-Mei Sun, Guo-Fang Fu, Yong-Zhong Du, Feng-Ying Chen, Hong Yuan, Cai-Hong Zheng, Xin-Mei Zhang, Fu-Qiang Hu, Gene therapy of endometriosis introduced by polymeric micelles with glycolipid-like structure Biomaterials. ,vol. 33, pp. 634- 643 ,(2012) , 10.1016/J.BIOMATERIALS.2011.09.077
Meng-Dan Zhao, Fu-Qiang Hu, Yong-Zhong Du, Hong Yuan, Feng-Ying Chen, Ya-Min Lou, He-Yong Yu, Coadministration of glycolipid-like micelles loading cytotoxic drug with different action site for efficient cancer chemotherapy. Nanotechnology. ,vol. 20, pp. 055102- ,(2009) , 10.1088/0957-4484/20/5/055102
Xiaolei Tang, Guijun Wang, Runjie Shi, Ke Jiang, Lingtong Meng, Hao Ren, Jinhui Wu, Yiqiao Hu, Enhanced tolerance and antitumor efficacy by docetaxel-loaded albumin nanoparticles Drug Delivery. ,vol. 23, pp. 2686- 2696 ,(2016) , 10.3109/10717544.2015.1049720
Francisca Tjhay, Takeshi Motohara, Shingo Tayama, Dashdemberel Narantuya, Koichi Fujimoto, Jianying Guo, Isao Sakaguchi, Ritsuo Honda, Hironori Tashiro, Hidetaka Katabuchi, CD44 variant 6 is correlated with peritoneal dissemination and poor prognosis in patients with advanced epithelial ovarian cancer. Cancer Science. ,vol. 106, pp. 1421- 1428 ,(2015) , 10.1111/CAS.12765
Ruth Perets, Ronny Drapkin, It's Totally Tubular....Riding The New Wave of Ovarian Cancer Research. Cancer Research. ,vol. 76, pp. 10- 17 ,(2016) , 10.1158/0008-5472.CAN-15-1382
Sunny Kumar, Siddharth S. Kesharwani, Himanshi Mathur, Mohit Tyagi, G. Jayarama Bhat, Hemachand Tummala, Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin. European Journal of Pharmaceutical Sciences. ,vol. 82, pp. 86- 96 ,(2016) , 10.1016/J.EJPS.2015.11.010
Mengdan Zhao, Jin-Lin Cheng, Jing-Jing Yan, Feng-Ying Chen, Jian-Zhong Sheng, Dong-Li Sun, Jian Chen, Jing Miao, Run-Ju Zhang, Caihong Zheng, He-Feng Huang, Hyaluronic acid reagent functional chitosan-PEI conjugate with AQP2-siRNA suppressed endometriotic lesion formation. International Journal of Nanomedicine. ,vol. 11, pp. 1323- 1336 ,(2016) , 10.2147/IJN.S99692
Gajanan Sathe, Sneha M. Pinto, Nazia Syed, Vishalakshi Nanjappa, Hitendra S. Solanki, Santosh Renuse, Sandip Chavan, Aafaque Ahmad Khan, Arun H. Patil, Raja Sekhar Nirujogi, Bipin Nair, Premendu Prakash Mathur, T. S. Keshava Prasad, Harsha Gowda, Aditi Chatterjee, Phosphotyrosine profiling of curcumin-induced signaling Clinical Proteomics. ,vol. 13, pp. 13- 13 ,(2016) , 10.1186/S12014-016-9114-0
Qing Yao, David C. Gutierrez, Ngoc Ha Hoang, Dongin Kim, Ruoning Wang, Christopher Hobbs, Lin Zhu, Efficient Codelivery of Paclitaxel and Curcumin by Novel Bottlebrush Copolymer-based Micelles Molecular Pharmaceutics. ,vol. 14, pp. 2378- 2389 ,(2017) , 10.1021/ACS.MOLPHARMACEUT.7B00278