A relationship between substance P receptor and retinal fibers in the rat suprachiasmatic nucleus
作者： Koichi Takatsuji , Emiko Senba , Patrick W. Mantyh , Masaya Tohyama
DOI: 10.1016/0006-8993(95)00802-W
关键词: Cell biology 、 Biology 、 Retinal 、 Endocrinology 、 Internal medicine 、 Substance P 、 Suprachiasmatic nucleus 、 Hypothalamus 、 Circadian rhythm 、 Central nervous system 、 Optic tract 、 Tachykinin receptor
摘要: The suprachiasmatic nucleus (SCN) in the hypothalamus controls many of circadian rhythms mammalian species. In present study, we investigated location substance P receptor (SPR)-containing neurons rat SCN, using a specific antibody against SPR, which corresponds to NK-1 subtype tachykinin receptors, and also examined synaptic relationship between SPR-containing retinal fibers at ultrastructural level. An SPR-immunoreactive meshwork labeled somata dendrites was identified SCN. strongest SPR-immunoreactivity observed dorsal lateral parts Many were there their protruded ventrally from somata. A few ventral part SCN within optic tract. eye-enucleated animals, degenerating shown terminate on forming asymmetrical axo-dendritic contacts.
elsevier.com
sci-hub.se 参考文章(23)
PW Mantyh, T Gates, CR Mantyh, JE Maggio, Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues The Journal of Neuroscience. ,vol. 9, pp. 258- 279 ,(1989) , 10.1523/JNEUROSCI.09-01-00258.1989
Shigenobu Shibata, Atsuko Tsuneyoshi, Toshiyuki Hamada, Keiko Tominaga, Shigenori Watanabe, Effect of substance P on circadian rhythms of firing activity and the 2-deoxyglucose uptake in the rat suprachiasmatic nucleus in vitro. Brain Research. ,vol. 597, pp. 257- 263 ,(1992) , 10.1016/0006-8993(92)91482-T
B Rusak, H. Robertson, W Wisden, S. Hunt, Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus Science. ,vol. 248, pp. 1237- 1240 ,(1990) , 10.1126/SCIENCE.2112267
Hiroshi Maeno, Hiroshi Kiyama, Masaya Tohyama, Distribution of the substance P receptor (NK-1 receptor) in the central nervous system Molecular Brain Research. ,vol. 18, pp. 43- 58 ,(1993) , 10.1016/0169-328X(93)90172-L
Tetsuo Shirakawa, Robert Y. Moore, Responses of rat suprachiasmatic nucleus neurons to substance P and glutamate in vitro Brain Research. ,vol. 642, pp. 213- 220 ,(1994) , 10.1016/0006-8993(94)90924-5
Koichi Takatsuji, Masaya Tohyama, Differential effects on substance P immunoreactivity in the rat suprachiasmatic and olivary pretectal nuclei Neuroreport. ,vol. 4, pp. 647- 650 ,(1993) , 10.1097/00001756-199306000-00011
Shyh Yuh Liou, Shigenobu Shibata, Katsunori Iwasaki, Showa Ueki, Optic nerve stimulation-induced increase of release of 3h-glutamate and 3h-aspartate but not 3h-gaba from the suprachiasmatic nucleus in slices of rat hypothalamus Brain Research Bulletin. ,vol. 16, pp. 527- 531 ,(1986) , 10.1016/0361-9230(86)90182-6
A.W. Duggan, P.J. Hope, B. Jarrott, H.-G. Schaible, S.M. Fleetwood-Walker, Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes Neuroscience. ,vol. 35, pp. 195- 202 ,(1990) , 10.1016/0306-4522(90)90134-P
Gérard Mick, Hiroshi Maeno, Hiroshi Kiyama, Masaya Tohyama, Marginal topography of neurons expressing the substance P receptor in the rat suprachiasmatic nucleus Molecular Brain Research. ,vol. 21, pp. 157- 161 ,(1994) , 10.1016/0169-328X(94)90388-3
H. Liu, J. L. Brown, L. Jasmin, J. E. Maggio, S. R. Vigna, P. W. Mantyh, A. I. Basbaum, Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 1009- 1013 ,(1994) , 10.1073/PNAS.91.3.1009