Regioselective deoxygenative CH trifluoromethylthiolation of heteroaryl N-oxides with AgSCF3
作者： Shi-Bo Zhang , Xiu-Hua Xu , Feng-Ling Qing
DOI: 10.1016/J.JFLUCHEM.2019.109367
关键词: Regioselectivity 、 Chemistry 、 Iodide 、 Medicinal chemistry
摘要: Abstract A mild and efficient method for the regioselective deoxygenative C H trifluoromethylthiolation of heteroaryl N-oxides with AgSCF3 is presented, employing p-toluenesulfonic anhydride tetra-n-butylammonium iodide as activators. This reaction delivers a series C2-trifluoromethylthiolated heteroaromatic compounds in moderate to excellent yields. It provides complementary reactions.
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