Pulmonary vascular structure in patients dying after a Fontan procedure. The lung as a risk factor.

作者: E Juaneda , S G Haworth

DOI: 10.1136/HRT.52.5.575

关键词: Vascular resistanceCardiologyMedicinePulmonary arteryAfterloadPulmonary hypertensionFontan procedureSurgeryHeart diseaseInternal medicineLungTricuspid valve

摘要: Pulmonary vascular structure was analysed in the lungs of 12 patients who had a Fontan repair, 11 whom died. Of eight with low pulmonary blood flow preoperatively, almost normal seven, but remaining patient many intra-acinar arteries contained organised occlusive thrombi. four an increased immediately before operation, there significant increase smooth muscle despite three having arterial band. The findings suggest that it is more difficult for to fulfil criteria and even when resistance less than 4 units/m2 may be abnormalities likely right atrial afterload prejudice outcome repair.

参考文章(10)
Rajendra Tandon, Jesse E. Edwards, Tricuspid atresia. A re-evaluation and classification. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 67, pp. 530- 542 ,(1974) , 10.1016/S0022-5223(19)40483-2
Viking O. Björk, Christian L. Olin, Björn B. Bjarke, Claes A. Thorén, Right atrial-right ventricular anastomosis for correction of tricuspid atresia. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 77, pp. 452- 458 ,(1979) , 10.1016/S0022-5223(19)40916-1
A W Gale, G K Danielson, D C McGoon, R B Wallace, D D Mair, Fontan procedure for tricuspid atresia. Circulation. ,vol. 62, pp. 91- 96 ,(1980) , 10.1161/01.CIR.62.1.91
D. Heath, J. W. DuShane, E. H. Wood, J. E. Edwards, The Aetiology of Pulmonary Thrombosis in Cyanotic Congenital Heart Disease with Pulmonary Stenosis Thorax. ,vol. 13, pp. 213- 217 ,(1958) , 10.1136/THX.13.3.213
D. F. Shore, J. Scallan, M. Leijala, E. A. Shinebourne, J. C. R. Lincoln, M. L. Rigby, O. D. H. Jones, The use of tolazoline hydrochloride as a pulmonary vasodilator in potentially fatal episodes of pulmonary vasoconstriction after cardiac surgery in children. Circulation. ,vol. 64, ,(1981)
Alan W. Gale, Gordon K. Danielson, Dwight C. McGoon, Douglas D. Mair, Modified Fontan operation for univentricular heart and complicated congenital lesions. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 78, pp. 831- 838 ,(1979) , 10.1016/S0022-5223(19)38027-4
Catherine Bull, Marc R. de Leval, Jaroslav Stark, James F.N. Taylor, Fergus J. Macartney, Dwight C. McGoon, Use of a subpulmonary ventricular chamber in the Fontan circulation The Journal of Thoracic and Cardiovascular Surgery. ,vol. 85, pp. 21- 31 ,(1983) , 10.1016/S0022-5223(19)38895-6
S G Haworth, M Rabinovitch, L M Reid, Z Vance, G Vawter, A R Castaneda, A S Nadas, Early pulmonary vascular changes in congenital heart disease studied in biopsy tissue. Human Pathology. ,vol. 11, pp. 499- 509 ,(1980)