Paliperidone for the treatment of schizoaffective disorder.
作者： Larry Alphs , Dong-Jing Fu , Ibrahim Turkoz
DOI: 10.1517/14656566.2016.1161029
关键词: Pediatrics 、 Population 、 Concomitant Therapy 、 Paliperidone 、 Paliperidone Palmitate 、 Mental illness 、 Schizoaffective disorder 、 Psychiatry 、 Psychosis 、 Medicine 、 Bipolar disorder
摘要: ABSTRACTIntroduction: Schizoaffective disorder (SCA) is a complex mental illness characterized by psychosis and affective symptoms. Treatment usually involves concomitant therapy with antipsychotics, mood stabilizers, and/or antidepressants. Effective treatment must address acute symptoms, maintain long-term stability, promote recovery, improve patient functioning.Areas covered: Data from 3 pivotal studies evaluating the maintenance of SCA paliperidone are reviewed. Two formulations have been studied for these indications: an extended-release oral formulation (NCT00397033, NCT00412373) long-acting injectable once-monthly palmitate (NCT01193153). The reported effects on psychotic, depressive, manic symptoms discussed.Expert opinion: Both were found to be safe effective SCA. Of critical importance this population that rapid improvement was s...
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