Fine Needle Aspiration Biopsy of Salivary Gland Lesions A Reappraisal of Pitfalls and Problems

摘要: Objective To assess the diagnostic value of fine needle aspiration biopsy in individual lesions salivary glands. Study design During a 16-year period (1979-1995), 841 gland were investigated by with cytologic examination. The affected parotid area all cases except 85 and 19, respectively, which submandibular oral cavity (more often palate) involved. Results Approximately 3% (25/841) aspirates inadequate, 97% they represented result samplings performed outside our institution. 816 comprised 245 negative for tumor cells (benign cysts, inflammatory, malformed, degenerative lesions), 571 positive (benign; malignant; not otherwise specified [NOS]); metastatic to tissue; or intraparotid periparotid lymph nodes). Among cells, 36 underwent surgery, absence neoplasm was histologically confirmed but one (a low grade mucoepidermoid carcinoma, underdiagnosed as retention cyst). patients having diagnosis 518 lesion removed nature confirmed. neoplastic demonstrated good correlation histology an oncocytic adenoma diagnosed Warthin's tumor, basal cell pleomorphic adenoma, carcinoma palate polymorphous adenocarcinoma vegetative intravascular hemangioendothelioma possible malignant NOS. Conclusion accuracy 97%, sensitivity presence 98% specificity 98%. Despite relative rarity tumors, if established criteria are present strictly observed, great majority common variants nonneoplastic both benign tumors can be high level accuracy. There remains proportion "problem cases" due lesions, these circumstances uncertainty must conveyed surgeon openly, leaving open, few suggested differential diagnoses.