Pediatric Plastic Bronchitis: Case Report and Retrospective Comparative Analysis of Epidemiology and Pathology

作者: Rebecca Kunder , Christian Kunder , Heather Y. Sun , Gerald Berry , Anna Messner

DOI: 10.1155/2013/649365

关键词: Standard treatmentMedicinePediatricsCase fatality ratePrevalencePathologyPneumoniaAirway obstructionEpidemiologyAsthmaHeart disease

摘要: Plastic bronchitis (PB) is a pathologic condition in which airway casts develop the tracheobronchial tree causing obstruction. There no standard treatment strategy for this uncommon condition. We report an index patient treated using emerging multimodal of directly instilled and inhaled tissue plasminogen activator (t-PA) as well 13 other cases PB at our institution between 2000 2012. The majority (n = 8) occurred patients with congenital heart disease. Clinical presentations, treatments used, histopathology casts, outcomes are reviewed. Further discussion focused on epidemiology plastic systematic approach to histologic classification casts. Comorbid conditions identified study included disease (8), pneumonia (3), asthma (2). Our institutional prevalence rate was 6.8 per 100,000 patients, case fatality 7%.

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