A Novel Sampling Model to Study the Epidemiology of Canine Leishmaniasis in an Urban Environment.

摘要: Background: Visceral leishmaniasis (VL) is one of the most important parasitic diseases in world. The domestic dog main reservoir zoonotic VL and a high prevalence canine (CanL) associated with transmission infection to humans. Here we describe methodology used obtain rapid representative sample dogs city Posadas, Misiones, compare Leishmania shelter dogs. Methodology: We land registry make random selection homes systematically recruited 349 from selected properties. also included all within city. Dogs were examined by two experienced veterinarians who recorded presence clinical signs common CanL using standardized protocol. extracted blood each performed four different serological tests reveal anti-Leishmania antibodies. Results: After examination, 145 (41.5%) 63 (90%) had compatible (p < 0.001). seroprevalence among was 20.1% (95% CI 16.1-24.6) which significantly lower than abandoned (38.6%, 95% 27.7-50.6, p spatial distribution infected fairly homogenous throughout Among dogs, observed positive association between where slept antibodies = 0.034). Of seropositive 38 (54.4%) asymptomatic. Conclusions: Our findings demonstrate how results can be highly influenced sampling methodology. estimate an urban setting, allowing decision makers deepen their understanding epidemiology timely efficient manner for development plans address both human disease.