The burden of chronic hepatitis B virus infection in Australia, 2011

摘要: Objective: The number of Australians living with chronic hepatitis B (CHB) is thought to be increasing, as are adverse outcomes including cirrhosis and liver cancer, however, robust, up-to-date estimates this burden limited. Contemporary the prevalence CHB in Australia essential guide appropriate public health clinical responses. Methods: This study used census-based methodology attributing risk by country birth Aboriginal Torres Strait Islander status, augmented priority risk-group based estimates. Deterministic mathematical modelling was for comparison validation census-derived estimates. Results: An estimated 218,000 (plausible range 192,000–284,000) CHB, a significant increase over previous derived using similar, at 204,000. Notable differences were observed geographic area both populations predominantly affected. It that only 56% people have been diagnosed notified. Conclusions: 1% population now majority experienced born overseas endemic areas, more than 95% new cases entering through migration. Implications: imperative attention greater resources devoted addressing Australia; proportion affected who on treatment, accordance First National Hepatitis Strategy.