5-year follow-up of a randomized controlled trial of immediate versus delayed zoledronic acid for the prevention of bone loss in postmenopausal women with breast cancer starting letrozole after tamoxifen: N03CC (Alliance) trial.

作者: Nina D. Wagner-Johnston , Jeff A. Sloan , Heshan Liu , Ann E. Kearns , Stephanie L. Hines

DOI: 10.1002/CNCR.29327

关键词: Randomized controlled trialAromataseBone densityTamoxifenBone Density Conservation AgentsMedicineZoledronic acidLetrozoleBreast cancerOncologyInternal medicine

摘要: Background Postmenopausal women with breast cancer (BC) receiving aromatase inhibitors are at increased risk for bone loss. The current study was undertaken to determine whether upfront versus delayed treatment zoledronic acid (ZA) impacted This report describes the 5-year follow-up results.

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