Control of muscle protein synthesis as a result of contractile activity and amino acid availability: implications for protein requirements.

摘要: The major anabolic influences on muscle are feeding and contractile activity. As a result of feeding, anabolism occurs chiefly by increases in protein synthesis with minor changes breakdown. Insulin has permissive role increasing synthesis, but the availability amino acids is crucial for net anabolism. We have investigated stimulating synergy between exercise acid availability, some signaling elements involved. results suggest that acutely sensitive to acids, probably effects separate pathway, this reason it unlikely accustomed physical requirements.