Pre-eclampsia and late fetal growth restriction.

摘要: There is a strong but complex relationship between fetal growth restriction and pre-eclampsia. According to the International Society for Study of Hypertension in Pregnancy co-existence gestational hypertension identifies pre-eclampsia with no need other signs maternal organ impairment. While early-onset are often strictly associated, such association becomes looser late preterm term periods. The incidence decreases dramatically from early (39-43%) (9-32%) finally (4-7%). Different placental cardiovascular mechanism underlie this trend: isolated has less frequent vascular lesions than associated pre-eclampsia; moreover, show different patterns cardiac output peripheral resistance comparison Consequently, current strategies first trimester screening dysfunction, originally implemented pre-eclampsia, do not perform well late-onset restriction: sensitivity combined small-for-gestational age newborns delivered at 32 weeks 56-63%, progressively those 32-36 (43-48%) or (21-26%). Moreover, while test more sensitive small-forgestational any age, its much lower without (31-37%) (19-23%).