Non-dermatophyte fungi in onychomycosis-Epidemiology and consequences for clinical practice.
作者： Dieter Reinel
DOI: 10.1111/MYC.13251
关键词: Combination therapy 、 Treatment regimen 、 Mixed infection 、 Dermatophyte 、 Epidemiology 、 Antifungal 、 Dermatology 、 Clinical Practice 、 Nail (anatomy) 、 Medicine
摘要: Onychomycoses are difficult-to-treat fungal infections with a high recurrence rate that relates to the anatomic and pathophysiological conditions in nail organ required extended duration of treatment. Clinical-epidemiological studies demonstrated non-dermatophyte molds yeasts primary causative agents 20%-30% onychomycoses. Mixed dermatophytes observed as well. Therefore, should be determined by culture antifungal treatment regimen reliably cover non-dermatophytes, if appropriate. Systemic-topical combination therapy involving broad-spectrum, locally applied may increase mycological clinical cure rates compared monotherapy systemic drugs.
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