Corticotropin-releasing factor immunoreactivity in post-mortem brain from depressed suicides.
作者： Bruce G. Charlton , Sharon C. Cheetham , Roger W. Horton , Cornelius L. E. Katona , M. Rufus Crompton
DOI: 10.1177/026988118800200103
关键词: Posterior parietal cortex 、 Brain tissue 、 Control subjects 、 Injury control 、 Accident prevention 、 Internal medicine 、 Poison control 、 Cerebrospinal fluid 、 Post mortem brain 、 Psychiatry 、 Endocrinology 、 Medicine
摘要: Corticotropin-releasing factor immunoreactivity (CRF-I) was measured in cortical brain tissue obtained at post-mortem from 12 suicide victims with clear evidence of depressive illness and age-matched sex-matched control subjects dying by natural causes. There were no significant differences mean CRF-I concentrations frontal, temporal, motor parietal cortex between the total group, or eight drug-free suicides their matched controls. These findings suggest that are unaltered discussed relation to recent reports elevated con centrations cerebrospinal fluid depressed patients.
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